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De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics
Non-protein coding RNAs (ncRNAs) make up the overwhelming majority of transcripts in the genome and have recently gained attention for their complex regulatory role in cells, including the regulation of protein-coding genes. Furthermore, ncRNAs play an important role in normal development and their...
Autores principales: | Fatemi, Roya Pedram, Velmeshev, Dmitry, Faghihi, Mohammad Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461991/ https://www.ncbi.nlm.nih.gov/pubmed/25405465 http://dx.doi.org/10.1038/mtna.2014.45 |
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