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Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis

INTRODUCTION: Systemic sclerosis (SSc) is a connective tissue disorder characterised by the development of skin fibrosis. Our current understanding of the disease pathogenesis is incomplete and the study of SSc is hindered, at least partially, by a lack of animal models that fully replicate the comp...

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Detalles Bibliográficos
Autores principales: Ruzehaji, Nadira, Avouac, Jerome, Elhai, Muriel, Frechet, Maxime, Frantz, Camelia, Ruiz, Barbara, Distler, Joerg H., Allanore, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461998/
https://www.ncbi.nlm.nih.gov/pubmed/26025306
http://dx.doi.org/10.1186/s13075-015-0659-5