Ubiquitin-specific protease 14 modulates degradation of cellular prion protein

Prion diseases are fatal neurodegenerative disorders characterized by the accumulation of prion protein (PrP(C)). To date, there is no effective treatment for the disease. The accumulated PrP, termed PrP(Sc), forms amyloid fibrils and could be infectious. It has been suggested that PrP(Sc) is abnorm...

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Detalles Bibliográficos
Autores principales: Homma, Takujiro, Ishibashi, Daisuke, Nakagaki, Takehiro, Fuse, Takayuki, Mori, Tsuyoshi, Satoh, Katsuya, Atarashi, Ryuichiro, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462021/
https://www.ncbi.nlm.nih.gov/pubmed/26061634
http://dx.doi.org/10.1038/srep11028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462021/
https://www.ncbi.nlm.nih.gov/pubmed/26061634
http://dx.doi.org/10.1038/srep11028

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