Expression and functional characterisation of System L amino acid transporters in the human term placenta

BACKGROUND: System L transporters LAT1 (SLC7A5) and LAT2 (SLC7A8) mediate the uptake of large, neutral amino acids in the human placenta. Many System L substrates are essential amino acids, thus representing crucial nutrients for the growing fetus. Both LAT isoforms are expressed in the human placen...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaccioli, Francesca, Aye, Irving L. M. H., Roos, Sara, Lager, Susanne, Ramirez, Vanessa I., Kanai, Yoshikatsu, Powell, Theresa L., Jansson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462079/
https://www.ncbi.nlm.nih.gov/pubmed/26050671
http://dx.doi.org/10.1186/s12958-015-0054-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462079/
https://www.ncbi.nlm.nih.gov/pubmed/26050671
http://dx.doi.org/10.1186/s12958-015-0054-8

Ejemplares similares