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Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences

BACKGROUND: Interleukin-22 (IL-22), a cytokine with important functions in anti-microbial defense and tissue repair, has been recently suggested to have beneficial effects in obesity and metabolic syndrome in some but not in other studies. Here, we re-examined the effects of IL-22 on obesity, insuli...

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Detalles Bibliográficos
Autores principales: Park, Ogyi, Ki, Sung Hwan, Xu, Mingjiang, Wang, Hua, Feng, Dechun, Tam, Joseph, Osei-Hyiaman, Douglas, Kunos, George, Gao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462081/
https://www.ncbi.nlm.nih.gov/pubmed/26064446
http://dx.doi.org/10.1186/s13578-015-0015-0