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Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences
BACKGROUND: Interleukin-22 (IL-22), a cytokine with important functions in anti-microbial defense and tissue repair, has been recently suggested to have beneficial effects in obesity and metabolic syndrome in some but not in other studies. Here, we re-examined the effects of IL-22 on obesity, insuli...
Autores principales: | Park, Ogyi, Ki, Sung Hwan, Xu, Mingjiang, Wang, Hua, Feng, Dechun, Tam, Joseph, Osei-Hyiaman, Douglas, Kunos, George, Gao, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462081/ https://www.ncbi.nlm.nih.gov/pubmed/26064446 http://dx.doi.org/10.1186/s13578-015-0015-0 |
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