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Mono-ethylhexyl phthalate stimulates prostaglandin secretion in human placental macrophages and THP-1 cells

BACKGROUND: Diethylhexyl phthalate (DEHP) is widely used as a plasticizer in polyvinyl chloride products. DEHP exposure, which is widespread in the US, increases preterm birth risk; however, the mechanisms driving this relationship are unclear. Because cyclooxygenase-2 (COX-2) dependent prostaglandi...

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Detalles Bibliográficos
Autores principales: Tetz, Lauren M, Aronoff, David M, Loch-Caruso, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462084/
https://www.ncbi.nlm.nih.gov/pubmed/26036283
http://dx.doi.org/10.1186/s12958-015-0046-8