Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein

In drug development, the toxicity of candidate chemicals must be carefully examined in an animal model. Here we developed a live imaging technique using silkworms for a noninvasive toxicity test applicable for drug screening. Injection of carbon tetrachloride, a tissue-injuring chemical, into transg...

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Detalles Bibliográficos
Autores principales: Inagaki, Yoshinori, Matsumoto, Yasuhiko, Ishii, Masaki, Uchino, Keiro, Sezutsu, Hideki, Sekimizu, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462092/
https://www.ncbi.nlm.nih.gov/pubmed/26061948
http://dx.doi.org/10.1038/srep11180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462092/
https://www.ncbi.nlm.nih.gov/pubmed/26061948
http://dx.doi.org/10.1038/srep11180

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