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Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism

BACKGROUND: Photoreceptor degeneration is a main hallmark of many blinding diseases making protection of photoreceptors crucial to prevent vision loss. Thus, regulation of endogenous neuroprotective factors may be key for cell survival and attenuation of disease progression. Important neuroprotectiv...

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Detalles Bibliográficos
Autores principales: Agca, Cavit, Boldt, Karsten, Gubler, Andrea, Meneau, Isabelle, Corpet, Armelle, Samardzija, Marijana, Stucki, Manuel, Ueffing, Marius, Grimm, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462110/
https://www.ncbi.nlm.nih.gov/pubmed/25907681
http://dx.doi.org/10.1186/s12915-015-0137-1