Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype

BACKGROUND: MMTV-Wnt1 transgenic mice develop mammary hyperplasia early in development, followed by the appearance of solitary mammary tumors with a high proportion of cells expressing early lineage markers and many myoepithelial cells. The occurrence of tumors is accelerated in experiments that act...

Descripción completa

Detalles Bibliográficos
Autores principales: Podsypanina, Katrina, Li, Yi, Varmus, Harold E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC446228/
https://www.ncbi.nlm.nih.gov/pubmed/15198801
http://dx.doi.org/10.1186/1741-7015-2-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC446228/
https://www.ncbi.nlm.nih.gov/pubmed/15198801
http://dx.doi.org/10.1186/1741-7015-2-24

Ejemplares similares