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Phase-1 study of abiraterone acetate in chemotherapy-naïve Japanese patients with castration-resistant prostate cancer

Persistent androgen synthesis under castration status in adrenal gland, testes and tumor cells is thought to be one of the major causes of development and progression of castration-resistant prostate cancer (CRPC). Abiraterone acetate (AA), the prodrug of abiraterone, which is an inhibitor of androg...

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Detalles Bibliográficos
Autores principales: Matsubara, Nobuaki, Uemura, Hiroji, Fukui, Iwao, Niwakawa, Masashi, Yamaguchi, Akito, Iizuka, Koho, Akaza, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462344/
https://www.ncbi.nlm.nih.gov/pubmed/25117615
http://dx.doi.org/10.1111/cas.12496