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Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress

Our previous study has shown that ampelopsin (AMP), a flavonol mainly found in Ampelopsis grossedentata, could induce cell death in human breast cancer cells via reactive oxygen species generation and endoplasmic reticulum (ER) stress pathway. Here, we examined whether autophagy is activated in AMP-...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Liang, Xinyu, Chang, Hui, Shu, Furong, Wu, Ying, Zhang, Ting, Fu, Yujie, Zhang, Qianyong, Zhu, Jun-Dong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462353/
https://www.ncbi.nlm.nih.gov/pubmed/25088800
http://dx.doi.org/10.1111/cas.12494