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Inhibition of metastasis of rhabdomyosarcoma by a novel neutralizing antibody to CXC chemokine receptor-4

Rhabdomyosarcoma is the most common soft tissue sarcoma affecting children, and the overall cure rate of children with metastatic disease remains below 30%. The CXC chemokine receptor-4 (CXCR4)/stromal cell-derived factor-1 (SDF1) axis has been implicated in the promotion of metastatic potential in...

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Detalles Bibliográficos
Autores principales: Kashima, Kenji, Watanabe, Miho, Sato, Yasuko, Hata, Junichi, Ishii, Nobuya, Aoki, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462355/
https://www.ncbi.nlm.nih.gov/pubmed/25154453
http://dx.doi.org/10.1111/cas.12490