Cargando…

Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation

Although it is known that ataxia-telangiectasia mutated (ATM) and interleukin 6 (IL-6) contribute to multiple drug resistance (MDR) in tumor chemotherapy, the exact role of ATM activation in MDR resulting from increased IL-6 expression is still unclear. In the present study, we demonstrate that the...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Hong Qiong, Huang, Xiao Bo, Ke, Shi Zhong, Jiang, Yi Na, Zhang, Yue Hua, Wang, Yi Nan, Li, Juan, Gao, Feng Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462389/
https://www.ncbi.nlm.nih.gov/pubmed/24988892
http://dx.doi.org/10.1111/cas.12478