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TET2 as an epigenetic master regulator for normal and malignant hematopoiesis

DNA methylation is one of the critical epigenetic modifications regulating various cellular processes such as differentiation or proliferation, and its dysregulation leads to disordered stem cell function or cellular transformation. The ten-eleven translocation (TET) gene family, initially found as...

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Detalles Bibliográficos
Autores principales: Nakajima, Hideaki, Kunimoto, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462392/
https://www.ncbi.nlm.nih.gov/pubmed/25040794
http://dx.doi.org/10.1111/cas.12484