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Prevention of cancer recurrence in tumor margins by stopping microcirculation in the tumor and tumor–host interface

Combretastatins interrupt blood flow of solid tumor vascular networks and lead to necrosis by blocking nutrients. However, tumors recover from tumor blood flow interruption-induced damage and develop viable rims. To investigate why cancer recurs and its prevention, we used a combretastatin derivativ...

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Detalles Bibliográficos
Autores principales: Hori, Katsuyoshi, Akita, Hirotoshi, Nonaka, Hiroi, Sumiyoshi, Akira, Taki, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462395/
https://www.ncbi.nlm.nih.gov/pubmed/24981848
http://dx.doi.org/10.1111/cas.12477