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Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer

Alternative polyadenylation (APA), which induces shortening of the 3′UTR, is emerging as an important phenomenon in gene regulation. APA is involved in development, cancer and cell proliferation. APA may lead to disruption of microRNA-mediated gene silencing in cancer cells via detachment of microRN...

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Detalles Bibliográficos
Autores principales: Ichinose, Junji, Watanabe, Kousuke, Sano, Atsushi, Nagase, Takahide, Nakajima, Jun, Fukayama, Masashi, Yatomi, Yutaka, Ohishi, Nobuya, Takai, Daiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462401/
https://www.ncbi.nlm.nih.gov/pubmed/24975429
http://dx.doi.org/10.1111/cas.12472