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Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer
Alternative polyadenylation (APA), which induces shortening of the 3′UTR, is emerging as an important phenomenon in gene regulation. APA is involved in development, cancer and cell proliferation. APA may lead to disruption of microRNA-mediated gene silencing in cancer cells via detachment of microRN...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462401/ https://www.ncbi.nlm.nih.gov/pubmed/24975429 http://dx.doi.org/10.1111/cas.12472 |