Structural Insight into an Alzheimer’s Brain-Derived Spherical Assembly of Amyloid β by Solid-State NMR

[Image: see text] Accumulating evidence suggests that various neurodegenerative diseases, including Alzheimer’s disease (AD), are linked to cytotoxic diffusible aggregates of amyloid proteins, which are metastable intermediate species in protein misfolding. This study presents the first site-specifi...

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Detalles Bibliográficos
Autores principales: Parthasarathy, Sudhakar, Inoue, Masafumi, Xiao, Yiling, Matsumura, Yoshitaka, Nabeshima, Yo-ichi, Hoshi, Minako, Ishii, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462565/
https://www.ncbi.nlm.nih.gov/pubmed/25938164
http://dx.doi.org/10.1021/jacs.5b03373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462565/
https://www.ncbi.nlm.nih.gov/pubmed/25938164
http://dx.doi.org/10.1021/jacs.5b03373

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