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Structural Insight into an Alzheimer’s Brain-Derived Spherical Assembly of Amyloid β by Solid-State NMR
[Image: see text] Accumulating evidence suggests that various neurodegenerative diseases, including Alzheimer’s disease (AD), are linked to cytotoxic diffusible aggregates of amyloid proteins, which are metastable intermediate species in protein misfolding. This study presents the first site-specifi...
Autores principales: | Parthasarathy, Sudhakar, Inoue, Masafumi, Xiao, Yiling, Matsumura, Yoshitaka, Nabeshima, Yo-ichi, Hoshi, Minako, Ishii, Yoshitaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462565/ https://www.ncbi.nlm.nih.gov/pubmed/25938164 http://dx.doi.org/10.1021/jacs.5b03373 |
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