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Sequence Polymorphism of Cytochrome b Gene in Theileria annulata Tunisian Isolates and Its Association with Buparvaquone Treatment Failure

BACKGROUND: Buparvaquone (BW 720C) is the major hydroxynaphtoquinone active against tropical theileriosis (Theileria annulata infection). Previous studies showed that buparvaquone, similarly to others hydroxynaphtoquinone, probably acts by binding to cytochrome b (cyt b) inhibiting the electron tran...

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Detalles Bibliográficos
Autores principales: Mhadhbi, Moez, Chaouch, Melek, Ajroud, Kaouthar, Darghouth, Mohamed Aziz, BenAbderrazak, Souha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462582/
https://www.ncbi.nlm.nih.gov/pubmed/26061414
http://dx.doi.org/10.1371/journal.pone.0129678