The Atypical Occurrence of Two Biotin Protein Ligases in Francisella novicida Is Due to Distinct Roles in Virulence and Biotin Metabolism

The physiological function of biotin requires biotin protein ligase activity in order to attach the coenzyme to its cognate proteins, which are enzymes involved in central metabolism. The model intracellular pathogen Francisella novicida is unusual in that it encodes two putative biotin protein liga...

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Detalles Bibliográficos
Autores principales: Feng, Youjun, Chin, Chui-Yoke, Chakravartty, Vandana, Gao, Rongsui, Crispell, Emily K., Weiss, David S., Cronan, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462617/
https://www.ncbi.nlm.nih.gov/pubmed/26060274
http://dx.doi.org/10.1128/mBio.00591-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462617/
https://www.ncbi.nlm.nih.gov/pubmed/26060274
http://dx.doi.org/10.1128/mBio.00591-15

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