Development of a Model System for Tick-Borne Flavivirus Persistence in HEK 293T Cells

We devised a model system to study persistent infection by the tick-borne flavivirus Langat virus (LGTV) in 293T cells. Infection with a molecularly cloned LGTV strain produced an acute lytic crisis that left few surviving cells. The culture was repopulated by cells that were ~90% positive for LGTV...

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Detalles Bibliográficos
Autores principales: Mlera, Luwanika, Offerdahl, Danielle K., Martens, Craig, Porcella, Stephen F., Melik, Wessam, Bloom, Marshall E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462619/
https://www.ncbi.nlm.nih.gov/pubmed/26045539
http://dx.doi.org/10.1128/mBio.00614-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462619/
https://www.ncbi.nlm.nih.gov/pubmed/26045539
http://dx.doi.org/10.1128/mBio.00614-15

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