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The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death

The tumour suppressor p53 is an important mediator of cell cycle arrest and apoptosis in response to DNA damage, acting mainly by transcriptional regulation of specific target genes. The exact details how p53 modulates this decision on a molecular basis is still incompletely understood. One mechanis...

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Detalles Bibliográficos
Autores principales: Bock, Florian J., Tanzer, Maria C., Haschka, Manuel D., Krumschnabel, Gerhard, Sohm, Bénédicte, Goetsch, Katrin, Kofler, Reinhard, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462756/
https://www.ncbi.nlm.nih.gov/pubmed/26062895
http://dx.doi.org/10.1038/srep11268