Cargando…
Development and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design
In this study, we developed and optimized a self-microemulsifying drug delivery system (SMEDDS) formulation for improving the dissolution and oral absorption of atorvastatin calcium (ATV), a poorly water-soluble drug. Solubility and emulsification tests were performed to select a suitable combinatio...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462857/ https://www.ncbi.nlm.nih.gov/pubmed/26089663 http://dx.doi.org/10.2147/IJN.S83520 |