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Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous niche

The complex relationship between tumour and stroma is still being elucidated but it is clear that cancer is a disease of more than just malignant cells. However, the dominant focus of our current understanding of Li Fraumeni Syndrome (LFS) remains on the function of p53 as ‘guardian of the genome’....

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Detalles Bibliográficos
Autor principal: Pantziarka, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462886/
https://www.ncbi.nlm.nih.gov/pubmed/26082798
http://dx.doi.org/10.3332/ecancer.2015.541