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Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous niche
The complex relationship between tumour and stroma is still being elucidated but it is clear that cancer is a disease of more than just malignant cells. However, the dominant focus of our current understanding of Li Fraumeni Syndrome (LFS) remains on the function of p53 as ‘guardian of the genome’....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cancer Intelligence
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462886/ https://www.ncbi.nlm.nih.gov/pubmed/26082798 http://dx.doi.org/10.3332/ecancer.2015.541 |