CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis

Free fatty acid induction of inflammation and cell death is an important feature of nonalcoholic steatohepatitis (NASH) and has been associated with disruption of the endoplasmic reticulum and activation of the unfolded protein response (UPR). After chronic UPR activation, the transcription factor C...

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Detalles Bibliográficos
Autores principales: Willy, Jeffrey A., Young, Sara K., Stevens, James L., Masuoka, Howard C., Wek, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462938/
https://www.ncbi.nlm.nih.gov/pubmed/25904325
http://dx.doi.org/10.1091/mbc.E15-01-0036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462938/
https://www.ncbi.nlm.nih.gov/pubmed/25904325
http://dx.doi.org/10.1091/mbc.E15-01-0036

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