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ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission

Aurora B regulates cytokinesis timing and plays a central role in the abscission checkpoint. Cellular events monitored by this checkpoint are beginning to be elucidated, yet signaling pathways upstream of Aurora B in this context remain poorly understood. Here we reveal a new connection between post...

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Detalles Bibliográficos
Autores principales: Mackay, Douglas R., Ullman, Katharine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462940/
https://www.ncbi.nlm.nih.gov/pubmed/25904336
http://dx.doi.org/10.1091/mbc.E14-11-1563