Cargando…

ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission

Aurora B regulates cytokinesis timing and plays a central role in the abscission checkpoint. Cellular events monitored by this checkpoint are beginning to be elucidated, yet signaling pathways upstream of Aurora B in this context remain poorly understood. Here we reveal a new connection between post...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mackay, Douglas R., Ullman, Katharine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462940/ https://www.ncbi.nlm.nih.gov/pubmed/25904336 http://dx.doi.org/10.1091/mbc.E14-11-1563

Ejemplares similares

Defects in nuclear pore assembly lead to activation of an Aurora B–mediated abscission checkpoint
por: Mackay, Douglas R., et al.
Publicado: (2010)

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission
por: Wenzel, Dawn M, et al.
Publicado: (2022)

A function for ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
por: Luessing, Janna, et al.
Publicado: (2022)

Mechanics and regulation of cytokinetic abscission
por: Andrade, Virginia, et al.
Publicado: (2022)

Contribution of integrin adhesion to cytokinetic abscission and genomic integrity
por: Rani, Bhavna, et al.
Publicado: (2022)

Tension-induced cytokinetic abscission in human fibroblasts
por: Gupta, Deepesh Kumar, et al.
Publicado: (2018)

Peptidyl-prolyl isomerization for cytokinetic abscission: Fold and cut
por: van der Horst, Armando, et al.
Publicado: (2012)

Septin and Ras regulate cytokinetic abscission in detached cells
por: Gupta, Deepesh Kumar, et al.
Publicado: (2019)

Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death
por: Stivers, Nicole S., et al.
Publicado: (2018)

Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis
por: Adar-Levor, Shai, et al.
Publicado: (2021)

Cytokinetic Abscission Regulation in Neural Stem Cells and Tissue Development
por: McNeely, Katrina C., et al.
Publicado: (2021)

ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo
por: Eikenes, Åsmund H., et al.
Publicado: (2015)

Identification of abscission checkpoint bodies as structures that regulate ESCRT factors to control abscission timing
por: Strohacker, Lauren K, et al.
Publicado: (2021)

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission
por: Uehara, Ryota, et al.
Publicado: (2016)

ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins
por: Caballe, Anna, et al.
Publicado: (2015)

Correction: ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo
Publicado: (2015)

An ATM–Chk2–INCENP pathway activates the abscission checkpoint
por: Petsalaki, Eleni, et al.
Publicado: (2020)

ESCRT Machinery Mediates Cytokinetic Abscission in the Unicellular Red Alga Cyanidioschyzon merolae
por: Yagisawa, Fumi, et al.
Publicado: (2020)

The mechanosensitive Piezo1 channel controls endosome trafficking for an efficient cytokinetic abscission
por: Carrillo-Garcia, Julia, et al.
Publicado: (2021)

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression
por: Di Benedetto, Anna, et al.
Publicado: (2017)

ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
por: Christ, Liliane, et al.
Publicado: (2016)

Resolving new ultrastructural features of cytokinetic abscission with soft-X-ray cryo-tomography
por: Sherman, Shachar, et al.
Publicado: (2016)

UMAD1 contributes to ESCRT-III dynamic subunit turnover during cytokinetic abscission
por: Glover, James, et al.
Publicado: (2023)

Abscission checkpoint control: stuck in the middle with Aurora B
por: Carmena, Mar
Publicado: (2012)

Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
por: Manic, Gwenola, et al.
Publicado: (2015)

Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells
por: Janisch, Kerstin M., et al.
Publicado: (2018)

Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death
por: Goliand, Inna, et al.
Publicado: (2014)

iASPP–PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation
por: Gao, Kun, et al.
Publicado: (2018)

The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge
por: Kumar, Harsh, et al.
Publicado: (2019)

PKCɛ switches Aurora B specificity to exit the abscission checkpoint
por: Pike, Tanya, et al.
Publicado: (2016)

Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer
por: Liu, Kang, et al.
Publicado: (2021)

Motor activity of centromere-associated protein-E contributes to its localization at the center of the midbody to regulate cytokinetic abscission
por: Ohashi, Akihiro, et al.
Publicado: (2016)

Targeting the ATR-CHK1 Axis in Cancer Therapy
por: Rundle, Stuart, et al.
Publicado: (2017)

Natural products targeting the ATR-CHK1 signaling pathway in cancer therapy
por: Ahmed, Salman, et al.
Publicado: (2022)

A novel role for the Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells
por: Sabbattini, Pierangela, et al.
Publicado: (2007)

The Aurora Kinase in Trypanosoma brucei Plays Distinctive Roles in Metaphase-Anaphase Transition and Cytokinetic Initiation
por: Li, Ziyin, et al.
Publicado: (2009)

APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors
por: Zong, Chunyan, et al.
Publicado: (2023)

Reed-Sternberg Cells Form by Abscission Failure in the Presence of Functional Aurora B Kinase
por: Xavier de Carvalho, Ana, et al.
Publicado: (2015)

Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells
por: Mordasini, Vanessa, et al.
Publicado: (2016)

Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
por: Yilmaz, Seçil, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_h7ajmej43k26mp48ivlhqel99d