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Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling
We examined the role of the actin-capping protein flightless I (FliI) in collagen remodeling by mouse fibroblasts. FliI-overexpressing cells exhibited reduced spreading on collagen but formed elongated protrusions that stained for myosin10 and fascin and penetrated pores of collagen-coated membranes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462945/ https://www.ncbi.nlm.nih.gov/pubmed/25877872 http://dx.doi.org/10.1091/mbc.E14-11-1536 |