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Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling

We examined the role of the actin-capping protein flightless I (FliI) in collagen remodeling by mouse fibroblasts. FliI-overexpressing cells exhibited reduced spreading on collagen but formed elongated protrusions that stained for myosin10 and fascin and penetrated pores of collagen-coated membranes...

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Detalles Bibliográficos
Autores principales: Arora, Pamma D., Wang, Yongqiang, Bresnick, Anne, Janmey, Paul A., McCulloch, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462945/
https://www.ncbi.nlm.nih.gov/pubmed/25877872
http://dx.doi.org/10.1091/mbc.E14-11-1536