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Wnt ligand–dependent activation of the negative feedback regulator Nkd1
Misregulation of Wnt signaling is at the root of many diseases, most notably colorectal cancer, and although we understand the activation of the pathway, we have a very poor understanding of the circumstances under which Wnt signaling turns itself off. There are numerous negative feedback regulators...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462952/ https://www.ncbi.nlm.nih.gov/pubmed/25904337 http://dx.doi.org/10.1091/mbc.E14-12-1648 |