Search for Human Lactate Dehydrogenase A Inhibitors Using Structure-Based Modeling

The human lactate dehydrogenase isoform A plays an important role in the anaerobic metabolism of tumour cells and therefore constitutes an attractive target in the oncology field. Full-atom models of lactate dehydrogenase A (in complex with NADH and in the apo form) have been generated to enable str...

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Detalles Bibliográficos
Autores principales: Nilov, D. K., Prokhorova, E. A., Švedas, V. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463413/
https://www.ncbi.nlm.nih.gov/pubmed/26085945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463413/
https://www.ncbi.nlm.nih.gov/pubmed/26085945

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