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Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting

B cells play a crucial role in the development and pathogenesis of systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce antibodies, but also secrete pro-inflammatory cytokines and present specific autoantigens to T cells. The treatment of autoimmune diseases via the...

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Detalles Bibliográficos
Autores principales: Stepanov, A. V., Belogurov Jr., A. A., Kothapalli, P., Shamborant, O. G., Knorre, V. D., Telegin, G. B., Ovsepyan, A. A., Ponomarenko, N. A., Deyev, S. M., Kaveri, S. V., Gabibov, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463415/
https://www.ncbi.nlm.nih.gov/pubmed/26085947