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Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting
B cells play a crucial role in the development and pathogenesis of systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce antibodies, but also secrete pro-inflammatory cytokines and present specific autoantigens to T cells. The treatment of autoimmune diseases via the...
Autores principales: | Stepanov, A. V., Belogurov Jr., A. A., Kothapalli, P., Shamborant, O. G., Knorre, V. D., Telegin, G. B., Ovsepyan, A. A., Ponomarenko, N. A., Deyev, S. M., Kaveri, S. V., Gabibov, A. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463415/ https://www.ncbi.nlm.nih.gov/pubmed/26085947 |
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