Insights on Structural Characteristics and Ligand Binding Mechanisms of CDK2

Cyclin-dependent kinase 2 (CDK2) is a crucial regulator of the eukaryotic cell cycle. However it is well established that monomeric CDK2 lacks regulatory activity, which needs to be aroused by its positive regulators, cyclins E and A, or be phosphorylated on the catalytic segment. Interestingly, the...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Jingxiao, Gao, Weimin, Zhang, Lilei, Pan, Yanqiu, Zhang, Shuwei, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463590/
https://www.ncbi.nlm.nih.gov/pubmed/25918937
http://dx.doi.org/10.3390/ijms16059314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463590/
https://www.ncbi.nlm.nih.gov/pubmed/25918937
http://dx.doi.org/10.3390/ijms16059314

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