Association between PDCD1 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus in Three Main Ethnic Groups of the Malaysian Population

The programmed cell death 1 (PDCD1) gene encodes for the PD-1 (programmed death 1) molecule, which negatively regulates self-reactive T- and B-cells in the maintenance of peripheral tolerance. A previous report had shown the development of lupus-like phenotypes in PD-1-deficient C57BL/6 mice, was su...

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Detalles Bibliográficos
Autores principales: Chua, Kek Heng, Lian, Lay Hoong, Sim, Xiu Jia, Cheah, Tien Eang, Lau, Tze Pheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463618/
https://www.ncbi.nlm.nih.gov/pubmed/25938972
http://dx.doi.org/10.3390/ijms16059794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463618/
https://www.ncbi.nlm.nih.gov/pubmed/25938972
http://dx.doi.org/10.3390/ijms16059794

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