Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process

Human mitochondrial DNA (mtDNA) is located in discrete DNA-protein complexes, so called nucleoids. These structures can be easily visualized in living cells by utilizing the fluorescent stain PicoGreen(®). In contrary, cells devoid of endogenous mitochondrial genomes (ρ(0) cells) display no mitochon...

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Detalles Bibliográficos
Autores principales: Schubert, Susanna, Heller, Sandra, Löffler, Birgit, Schäfer, Ingo, Seibel, Martina, Villani, Gaetano, Seibel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463621/
https://www.ncbi.nlm.nih.gov/pubmed/25941929
http://dx.doi.org/10.3390/ijms16059850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463621/
https://www.ncbi.nlm.nih.gov/pubmed/25941929
http://dx.doi.org/10.3390/ijms16059850

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