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Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process

Human mitochondrial DNA (mtDNA) is located in discrete DNA-protein complexes, so called nucleoids. These structures can be easily visualized in living cells by utilizing the fluorescent stain PicoGreen(®). In contrary, cells devoid of endogenous mitochondrial genomes (ρ(0) cells) display no mitochon...

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Detalles Bibliográficos
Autores principales:	Schubert, Susanna, Heller, Sandra, Löffler, Birgit, Schäfer, Ingo, Seibel, Martina, Villani, Gaetano, Seibel, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463621/ https://www.ncbi.nlm.nih.gov/pubmed/25941929 http://dx.doi.org/10.3390/ijms16059850

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