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Evolutionary Analysis of the B56 Gene Family of PP2A Regulatory Subunits

Protein phosphatase 2A (PP2A) is an abundant serine/threonine phosphatase that functions as a tumor suppressor in numerous cell-cell signaling pathways, including Wnt, myc, and ras. The B56 subunit of PP2A regulates its activity, and is encoded by five genes in humans. B56 proteins share a central c...

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Detalles Bibliográficos
Autores principales: Sommer, Lauren M., Cho, Hyuk, Choudhary, Madhusudan, Seeling, Joni M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463637/
https://www.ncbi.nlm.nih.gov/pubmed/25950761
http://dx.doi.org/10.3390/ijms160510134