Cargando…

4,4'-Diisothiocyanostilbene-2,2'-disulfonic Acid (DIDS) Ameliorates Ischemia-Hypoxia-Induced White Matter Damage in Neonatal Rats through Inhibition of the Voltage-Gated Chloride Channel ClC-2

Chronic cerebral hypoperfusion is believed to cause white matter lesions (WMLs), leading to cognitive impairment. Previous studies have shown that inflammation and apoptosis of oligodendrocytes (OLs) are involved in the pathogenesis of WMLs, but effective treatments have not been studied. In this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Baixiong, Quan, Hongyu, Ma, Teng, Tian, Yanping, Cai, Qiyan, Li, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463656/
https://www.ncbi.nlm.nih.gov/pubmed/25961953
http://dx.doi.org/10.3390/ijms160510457