Chitosan Oligosaccharides Inhibit/Disaggregate Fibrils and Attenuate Amyloid β-Mediated Neurotoxicity

Alzheimer’s disease (AD) is characterized by a large number of amyloid-β (Aβ) deposits in the brain. Therefore, inhibiting Aβ aggregation or destabilizing preformed aggregates could be a promising therapeutic target for halting/slowing the progression of AD. Chitosan oligosaccharides (COS) have prev...

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Detalles Bibliográficos
Autores principales: Dai, Xueling, Hou, Wanqi, Sun, Yaxuan, Gao, Zhaolan, Zhu, Shigong, Jiang, Zhaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463660/
https://www.ncbi.nlm.nih.gov/pubmed/26006224
http://dx.doi.org/10.3390/ijms160510526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463660/
https://www.ncbi.nlm.nih.gov/pubmed/26006224
http://dx.doi.org/10.3390/ijms160510526

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