Frequent Epigenetic Suppression of Tumor Suppressor Gene Glutathione Peroxidase 3 by Promoter Hypermethylation and Its Clinical Implication in Clear Cell Renal Cell Carcinoma

The goal of this study is to identify novel tumor suppressor genes silenced by promoter methylation in clear cell renal cell carcinoma (ccRCC) and discover new epigenetic biomarkers for early cancer detection. Reactive oxygen species (ROS) is a major cause of DNA damage that correlates with cancer i...

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Detalles Bibliográficos
Autores principales: Liu, Qianling, Jin, Jie, Ying, Jianming, Sun, Mengkui, Cui, Yun, Zhang, Lian, Xu, Ben, Fan, Yu, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463666/
https://www.ncbi.nlm.nih.gov/pubmed/25970749
http://dx.doi.org/10.3390/ijms160510636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463666/
https://www.ncbi.nlm.nih.gov/pubmed/25970749
http://dx.doi.org/10.3390/ijms160510636

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