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Mitochondria-Derived Reactive Oxygen Species Play an Important Role in Doxorubicin-Induced Platelet Apoptosis

Doxorubicin (DOX) is an effective chemotherapeutic agent; however; its use is limited by some side effects; such as cardiotoxicity and thrombocytopenia. DOX-induced cardiotoxicity has been intensively investigated; however; DOX-induced thrombocytopenia has not been clearly elucidated. Here we show t...

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Detalles Bibliográficos
Autores principales: Wang, Zhicheng, Wang, Jie, Xie, Rufeng, Liu, Ruilai, Lu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463691/
https://www.ncbi.nlm.nih.gov/pubmed/25988386
http://dx.doi.org/10.3390/ijms160511087