Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure

Background: Recent studies have linked histone deacetylases (HDAC) to remodeling of the heart and cardiac fibrosis in heart failure. However, the molecular mechanisms linking chromatin remodeling events with observed anti-fibrotic effects are unknown. Here, we investigated the molecular players invo...

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Detalles Bibliográficos
Autores principales: Nural-Guvener, Hikmet, Zakharova, Liudmila, Feehery, Lorraine, Sljukic, Snjezana, Gaballa, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463712/
https://www.ncbi.nlm.nih.gov/pubmed/25997003
http://dx.doi.org/10.3390/ijms160511482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463712/
https://www.ncbi.nlm.nih.gov/pubmed/25997003
http://dx.doi.org/10.3390/ijms160511482

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