Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21(WAF1) and WIP1 Expression

Phosphorylation of H2AX on Ser139 (γH2AX) after exposure to ionizing radiation produces nuclear foci that are detectable by immunofluorescence microscopy. These so-called γH2AX foci have been adopted as quantitative markers for DNA double-strand breaks. High numbers of spontaneous γH2AX foci have al...

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Wang, Ying W., Weiss, Robert H., Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463719/
https://www.ncbi.nlm.nih.gov/pubmed/26006237
http://dx.doi.org/10.3390/ijms160511609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463719/
https://www.ncbi.nlm.nih.gov/pubmed/26006237
http://dx.doi.org/10.3390/ijms160511609

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