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LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is an early event in the development of atheroscleros...

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Detalles Bibliográficos
Autores principales: Lillis, Anna P., Muratoglu, Selen Catania, Au, Dianaly T., Migliorini, Mary, Lee, Mi-Jeong, Fried, Susan K., Mikhailenko, Irina, Strickland, Dudley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463855/
https://www.ncbi.nlm.nih.gov/pubmed/26061292
http://dx.doi.org/10.1371/journal.pone.0128903