Cargando…

LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is an early event in the development of atheroscleros...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lillis, Anna P., Muratoglu, Selen Catania, Au, Dianaly T., Migliorini, Mary, Lee, Mi-Jeong, Fried, Susan K., Mikhailenko, Irina, Strickland, Dudley K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463855/ https://www.ncbi.nlm.nih.gov/pubmed/26061292 http://dx.doi.org/10.1371/journal.pone.0128903

Ejemplares similares

Correction: LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages
por: Lillis, Anna P., et al.
Publicado: (2016)

Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling
por: Au, Dianaly T., et al.
Publicado: (2018)

The LDL Receptor-Related Protein 1: At the Crossroads of Lipoprotein Metabolism and Insulin Signaling
por: Au, Dianaly T., et al.
Publicado: (2017)

Macrophage LRP1 Suppresses Neo-Intima Formation during Vascular Remodeling by Modulating the TGF-β Signaling Pathway
por: Muratoglu, Selen Catania, et al.
Publicado: (2011)

The LDL Receptor-Related Protein 1 (LRP1) Regulates the PDGF Signaling Pathway by Binding the Protein Phosphatase SHP-2 and Modulating SHP-2- Mediated PDGF Signaling Events
por: Craig, Julie, et al.
Publicado: (2013)

LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II–mediated signaling
por: Zhang, Jackie M., et al.
Publicado: (2023)

Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism
por: Cooper, Joanna M., et al.
Publicado: (2021)

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis
por: Xian, Xunde, et al.
Publicado: (2017)

LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells
por: Actis Dato, Virginia, et al.
Publicado: (2020)

Ectodomains of the LDL Receptor-Related Proteins LRP1b and LRP4 Have Anchorage Independent Functions In Vivo
por: Dietrich, Martin F., et al.
Publicado: (2010)

Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1
por: Kang, Liang-I, et al.
Publicado: (2015)

Electronegative LDL Promotes Inflammation and Triglyceride Accumulation in Macrophages
por: Puig, Núria, et al.
Publicado: (2020)

Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts
por: Chun, Haarin, et al.
Publicado: (2022)

Cellular Cholesterol Distribution Influences Proteolytic Release of the LRP-1 Ectodomain
por: Dekky, Bassil, et al.
Publicado: (2016)

When LDL Cholesterol Is Not LDL Cholesterol: LpX, A Clinical Lesson
por: Huygen, Lisa P.M., et al.
Publicado: (2022)

Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer
por: Pires, L.A., et al.
Publicado: (2012)

Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages
Publicado: (1995)

Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages
por: Vazquez, Matias M., et al.
Publicado: (2020)

Long non-coding RNA MALAT1 regulates cholesterol accumulation in ox-LDL-induced macrophages via the microRNA-17-5p/ABCA1 axis
por: Liu, Limin, et al.
Publicado: (2020)

The genetic and epigenetic association of LDL Receptor Related Protein 1B (LRP1B) gene with childhood obesity
por: Lee, Suman
Publicado: (2019)

LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB)
por: Shi, Xi, et al.
Publicado: (2022)

Elevated expression of cholesterol transporter LRP-1 is crucially implicated in the pathobiology of glioblastoma
por: N. R., Shruthi, et al.
Publicado: (2022)

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages
por: Ruuth, Maija, et al.
Publicado: (2018)

LRP4 LDLα repeats of astrocyte enhance dendrite arborization of the neuron
por: Yan, Min, et al.
Publicado: (2020)

Targeting LDL Cholesterol With LNA
por: Krieg, Arthur M
Publicado: (2012)

Cellular itinerary of LDL cholesterol
por: Vance, Jean E.
Publicado: (2022)

Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
por: Toledo, Juan, et al.
Publicado: (2016)

MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1
por: Yamamoto, Kazuhiro, et al.
Publicado: (2016)

Phytoplankton and Its Role in Accumulation of Microelements in Bottom Deposits of Azov Sea
por: Dotsenko, Irina V., et al.
Publicado: (2019)

Friedewald’s equation for calculating LDL-cholesterol: Is it the time to say “Goodbye” and adopt direct LDL cholesterol methods?
por: Khan, Sikandar Hayat, et al.
Publicado: (2019)

Cardiovascular mortality after intensive LDL-Cholesterol lowering: Does baseline LDL-Cholesterol really matter?
por: Khan, Safi U., et al.
Publicado: (2020)

LRP1 Controls cPLA(2) Phosphorylation, ABCA1 Expression and Cellular Cholesterol Export
por: Zhou, Li, et al.
Publicado: (2009)

Murine Missing in Metastasis (MIM) Mediates Cell Polarity and Regulates the Motility Response to Growth Factors
por: Yu, Dan, et al.
Publicado: (2011)

Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages
por: Lanuti, Mirko, et al.
Publicado: (2015)

Standardization of Apolipoprotein B, LDL‐Cholesterol, and Non‐HDL‐Cholesterol
por: Contois, John H., et al.
Publicado: (2023)

Correction: Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages
por: Lanuti, Mirko, et al.
Publicado: (2015)

Eugenol Reduces LDL Cholesterol and Hepatic Steatosis in Hypercholesterolemic Rats by Modulating TRPV1 Receptor
por: Harb, Amani A., et al.
Publicado: (2019)

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae
por: Kanai, Yoshimitsu, et al.
Publicado: (2014)

Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol
por: Trinh, Michael N., et al.
Publicado: (2022)

The effects of serum cholesterol, LDL, and HDL levels on gallstone cholesterol concentration
por: Atamanalp, S. Selcuk, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_07f042qegbhc70pfrva383knfg