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Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs

Classic semiquantitative proteomic methods have shown that all organisms respond to a mild heat shock by an apparent massive accumulation of a small set of proteins, named heat-shock proteins (HSPs) and a concomitant slowing down in the synthesis of the other proteins. Yet unexplained, the increased...

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Detalles Bibliográficos
Autores principales: Finka, Andrija, Sood, Vishal, Quadroni, Manfredo, Rios, Paolo De Los, Goloubinoff, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463922/
https://www.ncbi.nlm.nih.gov/pubmed/25847399
http://dx.doi.org/10.1007/s12192-015-0583-2