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Interactions of Human Autoantibodies with Hippocampal GABAergic Synaptic Transmission – Analyzing Antibody-Induced Effects ex vivo

Autoantibodies (aAB) to the presynaptic located enzyme glutamate decarboxylase 65 (GAD65) are a characteristic attribute for a variety of autoimmune diseases of the central nervous system including subtypes of limbic encephalitis, stiff person-syndrome, cerebellar ataxia, and Batten’s disease. Clini...

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Detalles Bibliográficos
Autores principales: Haselmann, Holger, Röpke, Luise, Werner, Christian, Kunze, Albrecht, Geis, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463933/
https://www.ncbi.nlm.nih.gov/pubmed/26124746
http://dx.doi.org/10.3389/fneur.2015.00136