PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells

It was previously reported that poly-(adenosine diphosphate-ribose) polymerase-1 (PARP-1) regulated ionizing radiation (IR)-induced autophagy in CNE-2 human nasopharyngeal carcinoma cells. The present study aimed to investigate whether PARP-1-mediated IR-induced autophagy occurred via activation of...

Descripción completa

Detalles Bibliográficos
Autores principales: CHEN, ZE-TAN, ZHAO, WEI, QU, SONG, LI, LING, LU, XIAO-DI, SU, FANG, LIANG, ZHONG-GUO, GUO, SI-YAN, ZHU, XIAO-DONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463980/
https://www.ncbi.nlm.nih.gov/pubmed/25872765
http://dx.doi.org/10.3892/mmr.2015.3604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463980/
https://www.ncbi.nlm.nih.gov/pubmed/25872765
http://dx.doi.org/10.3892/mmr.2015.3604

Ejemplares similares