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PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells
It was previously reported that poly-(adenosine diphosphate-ribose) polymerase-1 (PARP-1) regulated ionizing radiation (IR)-induced autophagy in CNE-2 human nasopharyngeal carcinoma cells. The present study aimed to investigate whether PARP-1-mediated IR-induced autophagy occurred via activation of...
Autores principales: | CHEN, ZE-TAN, ZHAO, WEI, QU, SONG, LI, LING, LU, XIAO-DI, SU, FANG, LIANG, ZHONG-GUO, GUO, SI-YAN, ZHU, XIAO-DONG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463980/ https://www.ncbi.nlm.nih.gov/pubmed/25872765 http://dx.doi.org/10.3892/mmr.2015.3604 |
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